“Chemical Biology elucidates the course and the modulation of molecular biological processes, including the interactions and functions of proteins, oligonucleotides, oligosaccharides, and secondary metabolites, by employing the power of chemical concepts and molecular probes. Chemical Biology research adopts state-of-the art methods such as computer-aided design, compound collections, molecular probing techniques, structural biology as well as latest analytical and screening technologies to identify new biologically active compounds or activity principles."
“ChemBioNet is a network of experts and resources to support primarily chemical biology projects in academic basic research ( http://www.chembionet.org). It serves as interdisciplinary communication and collaboration platform for chemists and biologists who want to use low molecular probes to unravel biological processes. Chemists from universities and large research institutes are pooling their collections in a central library where scientists can browse for bioactive compounds that help to characterize and investigate biological systems. The current library of about 35,000 compounds comprises commercially available and proprietary chemicals collected from members, and is systematically expanded. The screening facilities of the network offer modern infrastructure for high throughput screening experiments and diverse tools for the data analysis including interpretation by bioinformatics methods and virtual screening. The open screening platforms of the ChemBioNet enable the development of innovative high throughput screening assays. Joining forces with other chemical biology centers, ChemBioNet initiated a European infrastructure of open screening centers.”
Joint Working Group Chemical Biology – Gemeinsame Fachsektion Chemische Biologie
“The elucidation of biological processes by using small molecule probes, which influence protein functions and interactions, is at the heart of chemical biology. This interdisciplinary research field, for example, has great value for the systematic analysis of inter- and intracellular signalling pathways, providing the basis for the development of innovative new drugs.
Chemical biology requires the collaboration between organic chemists, molecular biologists, physicians, pharmacists, computer scientists and engineers. The German Pharmaceutical Society (Deutsche Pharmazeutische Gesellschaft e.V., DPhG), the Society for Biochemistry and Molecular Biology (Gesellschaft für Biochemie und Molekularbiologie e.V., GBM), the German Chemical Society (Gesellschaft Deutscher Chemiker e.V., GDCh) and the DECHEMA Society for Chemical Engineering and Biotechnology therefore founded the Joint Working Group Chemical Biology (Gemeinsame Fachgruppe Chemische Biologie, http://biotech.dechema.de/jwgcb.html). Currently, this group counts over 400 members.
The Joint Working Group Chemical Biology aims to bring together interested colleagues from universities, other public institutions and industry in joint research projects for the development and application of bioactive substances. The group founded and established ChemBioNet as an experts and resource network to support chemical biology in academic basic research. ChemBioNet is providing the necessary infrastructure in form of centralized screening centres. Currently, the Joint Working Group Chemical Biology supports the expansion of ChemBioNet into a European infrastructure within the framework of the ESFRI initiative "EU-OPENSCREEN".”
An information brochure can be down-loaded here in English or German:
Dr. Eberhard Krauß has been serving the board of the Joint Working Group Chemical Biology from 2006 – 2008, and again since January 2012.
Dr. Eberhard Krauß
www.chembiocon.de, Wiesbaden, Germany
www.chembiocon.com, Brussels area, Belgium